Stem Cell Therapy for Knee Osteoarthritis: Grades, Outcomes & Candidacy
Knee osteoarthritis (OA) is a degenerative joint condition that affects millions worldwide, leading to chronic pain, stiffness, and loss of function. While medications, physical therapy, and surgeries like knee replacement are common treatments, an increasing number of patients are exploring stem cell therapy as a regenerative option to delay or avoid invasive procedures.
✨ What Is Stem Cell Therapy for Knee OA?
Stem cell therapy uses regenerative cells—typically mesenchymal stem cells (MSCs)—derived from your own bone marrow or fat tissue to promote repair of cartilage, reduce inflammation, and potentially slow the progression of joint degeneration. These cells are injected directly into the affected knee, usually under ultrasound or fluoroscopic guidance.
📈 Outcomes Based on OA Grade
Knee OA is often graded using the Kellgren-Lawrence system (Grade 1 to 4):
- Grade 1: Minimal narrowing and small bone spurs. Early symptoms, ideal for regenerative intervention.
- Grade 2: Definite osteophytes and mild joint space narrowing. Many patients in this group respond well to stem cell therapy with improved mobility and pain reduction.
- Grade 3: Moderate narrowing, cartilage damage, and occasional deformity. Stem cells may offer symptom relief and delay surgical intervention.
- Grade 4: Severe cartilage loss, bone-on-bone contact. Results are variable; stem cell therapy may reduce inflammation but is not a replacement for joint replacement in many cases.
In clinical studies and our own experience at CRC, patients in Grades 1-3 show the most consistent improvement in pain, function, and overall quality of life.
🙋♂️ Who Is a Candidate?
Ideal candidates for knee stem cell therapy include:
- Men and women aged 35-75 with confirmed OA diagnosis
- Patients who have not responded to physical therapy or injections
- Individuals who want to avoid or delay surgery
- Patients with stable overall health
To find out if you qualify, complete our candidacy form for a free evaluation by our expert team.
👩⚕️ CRC’s Approach to Joint Regeneration
At Cellular Regeneration Clinic (CRC), we offer a comprehensive protocol including:
- High-purity MSC harvesting and processing in our certified lab
- Ultrasound-guided joint injections for precision delivery
- Optional adjuncts like PRP (Platelet-Rich Plasma) or exosomes
- Customized recovery and rehab plans
Our medical team includes orthopedic specialists and regenerative medicine experts who guide you through every step of the process.
🔄 Expected Results & Follow-Up
Most patients begin noticing improvement in pain and function within 1-3 months. Peak effects often appear around 6 months after therapy. Periodic assessments and possible booster treatments are discussed during follow-up visits.
While no therapy is universally effective, many of our patients report significant reduction in knee pain, improved walking distance, and better overall joint health—especially when therapy is performed in the earlier stages of OA.
❓ Common Questions
- Is stem cell therapy safe? Yes—when performed by trained professionals using autologous cells under sterile conditions.
- How long is recovery? Most patients resume light activity within 24-48 hours, and normal movement within a week.
- Will I still need a knee replacement? Some patients may eventually require surgery, but stem cell therapy can delay that need or improve quality of life in the meantime.
✨ Next Steps
If you or a loved one is dealing with knee osteoarthritis, stem cell therapy may offer a path to relief. Contact CRC today or see if you’re a candidate for our regenerative knee program.
Cellular Regeneration Clinic – Bringing science, care, and innovation to your knees.
